Skip directly to: Navigation for this section | Main page content

Bioinstrumentation and BioMEMS Laboratory

Photo

Weixiang is a postdoctoral researcher, with his research mainly focused on the application of chemometrics and bioinformatics methods to the design and implementation of novel analytical sensors. A wide spectrum of fields including environment protection and public health will be the direct beneficiary of these technologies.

Weixiang Zhao, Ph.D.

Postdoctoral Fellow

Education

B.S. Zhejiang University, China (1991-1995)

Biochemical Engineering

Ph.D. Zhejiang University, China (1995-2000)

Chemical Engineering

Honors and Awards

Excellent Score Scholarship (1992-1993)

Certificate of The Advanced Class for Basic Education (1994)

Guanghua Scholarship (1998)

Donggang Ph.D. Student Scholarship (1998-1999)

Tang Yongqian & Tang Yongnian Research Paper Prize (1999)

Academic Experience

  • Research Associate, Computer Science, Fudan University (Shanghai, China), 2000-2002
  • Research Associate, Chemical Engineering, Clarkson University (Potsdam, NY), 2002-2006

Internships, Co-Ops, Work Experience

  • Shandong Lukang Pharmaceutical Group Co. LTD. (With 7000 employees)
  • Sinopec Yizheng Chemical Fibre Company Limited, China. (The 4th largest polyester manufacturer in the world)
  • Sinopec Yangzi Petrochemical Company Ltd., China. (a top petrochemical company in China, yearly processing 8 million ton of crude oil)
  • U.S. Environmental Protection Agency
  • Collaboration with hospital clinicians for non-invasive disease diagnosis

Research Scopes

  • Chemo-, Bio-informatics
  • Spectroscopy Instrumentation Analysis
  • Sensor Design and Sensor Data Analysis for: Environmental Quality Analysis & Monitoring + Pollution & Disease Diagnosis
  • Metabolomics
  • Processes Analysis, Modeling, Control and Optimization

Technical Skills

  • Multivariate Statistical Analysis + Chemometrics
  • Data mining + Machine Learning
  • Pattern Recognition + Cluster Analysis
  • Numerical Modeling and Optimization
  • Time Series Analysis + Digital Signal Processing

Extracurricular Activities

  • Member of American Association for Aerosol Research
  • Member of Air & Waste Management Association (A&WMA)
  • Member of American Chemical Society (ACS)

Invited Referee For Peer-Reviewed Journals

  • Analytica Chimica Acta
  • Atmospheric Environment
  • Chemical Product and Process Modeling
  • Chemometrics and Intelligent Laboratory Systems
  • Chemosphere
  • Computers and Chemical Engineering
  • Engineering Optimization
  • IEEE Sensors Journal
  • Journal of Chemometrics
  • Journal of Geophysical Research - Atmospheres
  • Journal of Sensors
  • Journal of the Air & Waste Management Association
  • Science of the Total Environment

Publications (1): Invited Book Chapters

  1. Weixiang Zhao and Cristina E. Davis, (2007). "Pattern recognition algorithms to analyze data outputs for novel E-nose sensors", Pattern Recognition in Nanoscience, Environmental Engineering and Archeology, (Editor: Diane M. Perez), Nova Science Publishers.
  2. Yijun He, Dezhao Chen, Weixiang Zhao, (2007). "Integration Method of Ant Colony Algorithm and Rough Set Theory for Simultaneous Real Value Attribute Discretization and Attribute Reduction", Swarm Intelligence: Focus on Ant and Particle Swarm Optimization (Editor: Felix T. S. Chan and Manoj Kumar Tiwari), I-Tech Education and Publishing.

Publications (2): Peer Reviewed Journal Papers ([cn]: Chinese Journal. Totally 4)

  1. Weixiang Zhao, Cristina E. Davis (2009). Swarm intelligence based wavelet coefficient feature selection for mass spectral classification: an application to proteomics data. Analytica Chimica Acta (In press).
  2. Weixiang Zhao, Shankar Sankaran, Ana Maria Ibanez, Abhaya M. Dandekar, Cristina E. Davis (2009). Two-dimensional Wavelet Analysis Based Classification of Gas Chromatogram Differential Mobility Spectrometry Signals. Analytica Chimica Acta. 647: 46-53.
  3. Weixiang Zhao, Cristina E. Davis (2009). Autoregressive model based feature extraction method for time shifted chromatography data. Chemometrics and Intelligent Laboratory Systems. 96: 252-257.
  4. Shaohui Tao, Dezhao Chen, Weixiang Zhao (2009). Fast pruning algorithm for multi-output LS-SVM and its application in chemical pattern classification. Chemometrics and Intelligent Laboratory Systems. 96: 63-69.
  5. Liming Zhou, Philip K. Hopke, Weixiang Zhao (2009). Source Apportionment of Airborne Particulate Matter for The Speciation Trends Network Site in Cleveland, OH. Journal of the Air & Waste Management Association. 59:321-331.
  6. Weixiang Zhao, Abhinav Bhushan, Anthony D. Santamaria, Melinda G. Simon and Cristina E. Davis, (2008). Machine Learning: A Crucial Tool for Sensor Design. Algorithms. 1(2):130-152.
  7. Weixiang Zhao, Joshua T. Morgan and Cristina E. Davis, (2008). Gas Chromatography Data Classification Based on Complex Coefficients of an Autoregressive Model. Journal of Sensors. (2008), doi:10.1155/2008/262501
  8. Mary A. Molina*, Weixiang Zhao* (*: joint first authors), Shankar Sankaran, Michael Schivo, Nicholas Kenyon, Cristina E. Davis, (2008). Design-of-Experiment Optimization of Exhaled Breath Condensate Analysis Using a Miniature Differential Mobility Spectrometer (DMS). Analytica Chimica Acta, Vol. 628, 155-161.
  9. Susan Ayer*, Weixiang Zhao* (*: joint first authors), and Cristina E. Davis, (2008). Differentiaion of Proteins and Viruses Using Pyrolysis Gas Chromatography Differential Mobility Spectrometry (PY/GC/DMS) and Pattern Recognition. IEEE Sensors Journal, Vol. 8, No. 9, 1586-1592.
  10. Weixiang Zhao, Philip K. Hopke, Kimberly A. Prather, (2008). Comparison Of Two Cluster Analysis Methods using Single Particle Mass Spectra. Atmospheric Environment Vol. 42, 881-892.
  11. Yijun He, Dezhao Chen, Weixiang Zhao, (2008). Integrated Method of Compromise-based Ant Colony Algorithm and Rough Set Theory and Its Application in Toxicity Mechanism Classification. Chemometrics and Intelligent Laboratory Systems. Vol. 92, 22-32.
  12. Xuefeng Yan, Weixiang Zhao, (2009). 4-CBA concentration soft sensor based on modified back propagation algorithm embedded with ridge regression. Intelligent Automation and Soft Computing. Vol. 15, No. 1, 41-51.
  13. Weixiang Zhao, Philip K. Hopke, ErwinW. Gelfand, and Nathan Rabinovitch, (2007). Use of an expanded receptor model for personal exposure analysis in schoolchildren with asthma. Atmospheric Environment. Vol. 41, 4084-4096.
  14. Weixiang Zhao, Philip K. Hopke, Liming Zhou, (2007). Spatial distribution of source locations for particulate nitrate and sulfate in the upper-midwestern United States. Atmospheric Environment Vol. 41, 1831-1847.
  15. Matthew Strand, Philip K. Hopke, Weixiang Zhao, Sverre Vedal, Erwin Gelfand, Nathan Rabinovitch, (2007). A study of health effect estimates using competing methods to model personal exposures to ambient PM2.5. Journal of Exposure Science and Environmental Epidemiology. Vol. 17, 549-558.
  16. Weixiang Zhao, Philip K. Hopke, Gary Norris, Ron Williams, and Pentti Paatero, (2006). Source Apportionment and Analysis on Ambient and Personal Exposure Samples with a Combined Receptor Model and an Adaptive Blank Estimation Strategy. Atmospheric Environment Vol. 40, 3788-3801.
  17. [cn] Xuefeng Yan, Weixiang Zhao (2006). RBF-APLSR Is Employed to Design the Substituted Aromatic Sulfur Derivatives Molecular Structure. Computers and Applied Chemistry (Chinese Journal). 23, (9), 801-805.
  18. Weixiang Zhao, Philip K. Hopke, (2006). Source Identification for Fine Aerosols in Mammoth Cave National Park. Atmospheric Research. Vol. 80, 309-322.
  19. Weixiang Zhao, Philip K. Hopke, (2006). Source Investigation for Ambient PM2.5 in Indianapolis, IN. Aerosol Science & Technology. 40, 898-909.
  20. Xuefeng Yan, Weixiang Zhao, (2006). A Novel Select-best and Prepotency Evolution Algorithm and Its Application to Develop Industrial Oxidation Reaction Macrokinetic Model. Computers and Chemical Engineering. Vol. 30, 807-815.
  21. Yijun He, Dezhao Chen, Weixiang Zhao, (2006). Ensemble Classifier System Based on Ant Colony Algorithm and Its Application in Chemical Pattern Classification. Chemometrics and Intelligent Laboratory Systems. Vol. 80, 39-49.
  22. Weixiang Zhao, Philip K. Hopke, Xueying Qin, and Kimberly A. Prather, (2005). Predicting bulk ambient aerosol compositions from ATOFMS data with ART-2a and multivariate analysis. Analytica Chimica Acta. Vol. 549, 179-187.
  23. Bing Zhang, Dezhao Chen, and Weixiang Zhao, (2005). Iterative Ant-colony Algorithm and Its Application to Dynamic Optimization of Chemical Process. Computers and Chemical Engineering. Vol. 29, 2078-2086.
  24. Bilkis A. Begum, Philip K. Hopke, and Weixiang Zhao, (2005). Source identification of fine particles in Washington DC by expanded factor analysis modeling. Environmental Science & Technology. Vol. 39, 1129-1137.
  25. Weixiang Zhao, Dezhao Chen, and Shangxu Hu, (2004). Detection of outlier and a robust BP algorithm against outlier. Computers and Chemical Engineering. Vol. 28, 1403-1408.
  26. Weixiang Zhao and Philip K. Hopke, (2004). Source Apportionment for Ambient particles in the San Gorgonio Wilderness. Atmospheric Environment Vol. 38, 5901-5910.
  27. Weixiang Zhao, Philip K. Hopke, and Thomas Karl, (2004). Source identification of volatile organic compounds in Houston, Texas. Environmental Science & Technology. Vol. 38, 1338-1347.
  28. D. B. Kittelson, W. F. Watts, J. P. Johnson, M. L. Remerowki, E. E. Ische, G. Oberdörster, R. M. Gelein, A.C. Elder, P. K. Hopke, E. Kim, W. Zhao, L. Zhou, and C.-H. Jeong (2004). On-Road Exposure to Highway Aerosols. 1. Aerosol and Gas Measurements. Inhalation Toxicology Vol. 16, 31-39.
  29. Alison Elder, Robert Gelein, Jacob Finkelstein, Richard Phipps, Mark Frampton, Mark Utell, David B. Kittelson, Winthrop F. Watts, Philip Hopke, Cheol-Heon Jeong, Eugene Kim, Wei Liu, Weixiang Zhao, Liming Zhuo, Renaud Vincent, Premkumari Kumarathasan, and Gunter Oberdorster, (2004). On-Road Exposure to Highway Aerosols. 2. Exposures of Aged, Compromised Rats. Inhalation Toxicology Vol. 16, 41-53.
  30. [cn] Weixiang Zhao, Lide Wu, (2002). RBFN Structure Determination Based on PLS and GAs. Journal of Software (Chinese Journal). Vol. 13, No. 8, 1450-1455.
  31. Weixiang Zhao, Dezhao Chen, Shangxu Hu, (2002). Differential fraction based kinetic model for simulating hydrodesulfurization process of petroleum fraction. Computers and Chemistry. Vol. 26, No. 2, 141-148.
  32. [cn] Ling Zhuang, Dezhao Chen, Weixiang Zhao and Shangxu Hu, (2002). RBF-CSR approach and the study on its application to modeling the cracking equipments. Journal of Chemical Engineering of Chinese Universities (Chinese Journal). Vol. 16, No. 1, 64-69.
  33. Weixiang Zhao, Dezhao Chen and Shangxu Hu, (2000). Optimizing Operating Conditions Based On ANN and Modified GAs. Computers and Chemical Engineering. Vol. 24, No. 1, 61-65.
  34. [cn] Weixiang Zhao, Dezhao Chen and Shangxu Hu, (1999). Potential RBF Networks and Its Application in Water Quality Diagnosis. Journal of Zhejiang University (Chinese Journal). Vol. 33, No.2, 147-151.
  35. Zhao Weixiang, Chen Dezhao and Hu Shangxu, (1998). Potential Function Based Neural Networks and Its Application to the Classification of Complex Chemical Patterns. Computers and Chemistry. Vol. 22, No. 5, 385-391.

Publications (3): Peer Reviewed Conference Papers

  1. Weixiang Zhao and Lide Wu, (2001). Integration of ANN and Statistical Method for Outlier Detection in Complex System. The 8th International Conference on Neural Information Processing, 2001. 1614-1619.
  2. Sankaran S, Zhao W, Loyola B, Morgan J, Molina M, Shivo M, Rana R, Kenyon N, Davis CE. (2007). Microfabricated differential mobility spectrometers for breath analysis. Sensors, 2007 IEEE. 16-19.

Selected Presentations (out of 12)

  1. Clinical and Translational Science Center and Center for Biophotonics Science and Technology Workshop, 2008. Presented: “Adaptation of Machine Learning Algorithms for Spectrometer Data Analysis”
  2. American Association for Aerosol Research Annual Conference, 2006. Presented: “Use of an Expanded Receptor Model for Personal Exposure Analysis in Urban Schoolchildren with Asthma”
  3. American Association for Aerosol Research Annual Conference, 2006. Presented: “Investigating Spatial Distribution of Origins for Nitrate and Sulfate in Midwestern Areas via SQTBA and RTWC”
  4. American Association for Aerosol Research Annual Conference, 2004. Presented: “Predicting bulk ambient aerosol compositions from ATOFMS data”
  5. Trilinear Methods in Chemistry and Psychology (TRICAP) 2003. Presented: “Source identification of volatile organic compounds in Houston, TX”
  6. American Association for Aerosol Research, Particulate Matter: Atmospheric Science, Exposure and the Fourth Colloquium on PM and Human Health, 2003. Presented: “Separating diesel and spark-ignition vehicle particles in the San Gorgonio National Monument”