Mei-Lin's Research
Bioassays based on magnetic recording technology
Introduction
This project aims to develop a magnetic scanning probe microscope based on
a magnetic tunnel junction (MTJ) sensor for the detection of
magnetically-labeled biomolecules. Paramagnetic particles are employed as
markers and incorporated with commercial DNA microarray technology to
produce magnetically labeled DNA microarrays. An external magnetic tunnel
junction is mechanically scanned across these arrays to detect and map out
the localized magnetic fields from these particles. This new approach
offers the potential to image centimeterscale arrays of thousands of DNA
spots while still achieving the micron-scale spatial resolution required
to image individual magnetic markers.